Pirfenidone CAS 53179-13-8 Factory Supply Piresupa
Basic Information:
HP9012 Pirfenidone Assay: 98.5%~101.0% CAS53179-13-8 Fresh stock |
| Pirfenidone | CAS 53179-13-8 | Brand: Network Union |
| MW: 185.22 | MSDS: Avaiable |
| MF : C12H11NO | Sample: Avaiable |
| Category:Antiinflammatory Agents | Min order: 10grams |
| Quality standard : Enterprise standard | Place of Origin:China |
| Introduction | Uses: The new anti-fibrotic material, with broad-spectrum anti-lung, liver, kidney, heart, and peritoneal fibrosis |
| Character | White powder |
| Applications | Pharmaceutical raw materials |
Introduction:
In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.
Specification:
Item |
Standard |
Appearance |
White crystal powder |
Melting Point |
102--109°C |
Loss on drying |
<1.0% |
Known single impurity |
<1.0% |
Unknown single impurity
|
<0.5% |
Total impurity
|
<2.0% |
Assay(as dried) |
99% |
Application:
In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.
Package , Shipping and Delivery:
Package:
0.5kgs/Al-foil bag
1.0kgs/Al-foil bag
2.0kgs/Al-foil bag
5.0 kgs/Al-foil bag
25.0 kgs/drum
or upon customers' request.
24 months at normal temperature, drying and sealed conditions.
Shipping: Air Express
Delivery: Within 3 days after get the payment
Packaging & Delivery:
We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.
Our advantages:
Our company is a professional raw powder factory in China for over 10 years, all powders are factory directly supplying.
Our products have exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Australia, Japan, Korea and many other countries, over 100kgs each month.
Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed. 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98% pass to Germany, Russia, Australia, New Zealand.
Most of powders are in stock, Chargeable samples are available, Could be shipped out within 24hours.
High quality, good price, fast and safety delivery. Shipment by DHL, TNT, FEDEX, HKEMS, UPS, etc.
Wuhan Wang Lianshang Biotechnology Co., Ltd. is a leading Chinese chemical supplier specializing in fine chemical, flavor, food additive, pharmaceutical intermediates.
The company invests large fund and brains to R&D department to research fine chemical, biochemical, pharmaceutical & its intermediates products that fit the demand of the market. High level research group, advanced apparatus and good scientific atmosphere ensure the quality of R&D. All the products in plant are the fruit of R&D department. Our products reach the advanced standard of domestic market, many of which reach the international standard.
The company capital asserts is above 100 million RMB. According to the GMP standard, the company has built 10000 m2 plant equipped the advanced equipment. The factory has a complete Q. A. & Q. C. System. We own several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and UV spectrophotometer to analyze and control the products. The company has gotten the approval of ISO9001. We have the authority of export and import biochemical, pharmaceutical & steroid hormone, pharmaceuical intermediates distributed by the company are sold both in the domestic and international market and highly recommended by our clients. In order to develop the market further, we are eager to cooperate with the manufactory and trading company around the globe to make a prosperous future.
We advocate a enterprise idea that"people first, lead in the development of science and technology, serving society", insist on taking the road that"link science and technology as a marriage ", base on high-standard, new technologe, high quality. We have one batch the high-tech talent who are the chemical industry manages, produces, develops, all kinds of professional and technical personnel's account for 30% of the total number of company, is devoted to research, development, production of the new high-tech product, introduce the products innovated constantly to the market. We own several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and UV spectrophotometer to analyze and control the products. The company has gotten the approval of ISO9001.
Our Staff will pursue high quality and perfect brand with untiring efforts, and inherit enterprising spirit on"candid, diligent, refinement, upwards", follow the enterprise management theory of"lives, services or soul of quality ", with the first-class products and high-quality service to meet market's demands.
