Naringin (CAS: 10236-47-2)
Testing Method: HPLC
Molecular formula: C27H32O14
Molecular weight: 580.53
CAS: 10236-47-2
Origin: Citrus Paradisi Macfadyen, pomelo extract, Natrual citrus fruit extract naringin, plant extract powder, flavonoids
Specification: 98% Naringin
Physical property:
It is a white to light yellow crystalline powder. Crystallization in water containing 6-8 crystal water and crystal, the temperature of 83 ° C and 110 ° C in drying to constant weight in containing two of the crystal water Commodities, melting point 171 ° C Great pains, water diluted to 1: 10 still perlingual. 1g the goods 1000ml water soluble; 1g the materials can be dissolved in 10ml of 75 ° C water. Soluble acetone, ethanol and warmed to the glacial acetic acid.
Naringin Functions:
1. Cholesterol-lowering effect, help treating diabetes, Naringin (and grapefruit) can interfere with certain drugs including calcium channel blockers, sedatives, cholesterol lowering drugs, and estrogen.
2. Naringin stimulates the effect could therefore increase its fat burning action.
Indications and Usage:
1. Naringin exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of selected drug-metabolizing cytochrome P450 enzymes, including CYP3A4 and CYP1A2, which may result in drug-drug interactions in vivo. Ingestion of naringin and related flavonoids can also affect the intestinal absorption of certain drugs, leading to either an increase or decrease in circulating drug levels. To avoid interference with drug absorption and metabolism, the consumption of citrus (esp. Grapefruit) and other juices with medications is contraindicated.
2. Naringin, followed by rutin, was the most potent flavonoid inhibitor of VEGF release, which causes angiogenesis, out of 21 flavonoids.
3. When naringin is treated with potassium hydroxide or another strong base, and then catalytically hydrogenated, it becomes a naringin dihydrochalcone, a compound roughly 300-1800 times sweeter than sugar at threshold concentrations.
Nanjing ZeLang Medical Technology Co. Ltd specializes in researching and manufacturing of botanical, herbal and plant extracts in China. Depending on China Pharmaceutical University and Nanjing university, our company possesses a strong technology team mainly made of the talented with Master s Degree, and employs a number of professors who are specialists in Medicine chemical industry as our technology consultants all the year round.
Today, the demand for ZeLang's services has never been greater. Intense competition, pricing pressures, and suppy shortages are challenging our customers to make important global supply decisions more effectively and efficiently. Increasing competitive advantage and cost savings without sacrifice of quality has become paramount. This is why some of todays's highly reculated industries such as Pharmaceutical, Cosmetic & Personal Care and Industrial have turned to ZeLang.
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