Product Name: trilostane
Alias: Trilostane; Vetoryl; Modrastane; Desopan; modrenal;
CAS No .: 13647-35-3
Molecular Formula: C20H27NO3
Molecular Weight: 329.43300
Accurate Mass: 329.19900
PSA: 76.78000
LogP: 3.46688
Appearance and Properties: Tawny Crystal
Density: 1.25g / cm3
Melting Point: 264ºC
Boiling Point: 516.5ºC at 760 mmHg
Flash Point: 266.1ºC
Refractive Index: 1.61
Vapor Pressure: 5.39E-12mmHg at 25 ° C
Customs Code: 2937290090
use
Troxantin is a new anti-estrogen drug with a novel mechanism of action for the treatment of breast cancer. Triostein can inhibit 3β-dehydrogenase during corticosteroid synthesis and reduce the synthesis of cortisol and aldosterone, and is clinically used to treat Cushing's syndrome (Cushing's syndrome) and primary aldosteronism. However, Shin syndrome (cortisol hypersemphism) is less effective than metilazokone. This product also significantly reduce the role of serum testosterone levels may be related to the inhibition of their synthesis.
Product name |
Trilostane |
CAS
CAS No. |
13647-35-3 |
Outer Packing |
1KG |
Production date |
Nov.03th,2016 |
Shelf life |
Nov.02th,2019 |
Standard adopted |
Enterprise Standard |
Items of analysis |
Specification |
Results |
Identification |
Positive |
Confirm |
Appearance |
White to pale white solid |
white solid |
Melting point |
257°C to 270°C |
261°C -267°C |
Heavy metals |
No more than 20ppm |
10ppm |
Loss on drying |
Not more than 0.5% |
0.15% |
Residue on ignition |
Not more than 0.1% |
0.020% |
Solubility |
soluble in dimethyl sulfoxide;soluble in pyridine;slightly soluble in ethanol;slightly soluble in water |
conforms |
Assay |
Not less than 99.0% |
99.6% |
Specific Rotation |
+137-139° |
137.5° |
ated impurities |
not more than 1.0% |
0.35% |
HPLC purity |
not less than 99.0% |
99.6% |
Solvent Residues |
Ethanol<5000ppm |
1000ppm |
Conclusion |
Qualified |
Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. Was founded in 2013, a branch of "Yuancheng" Group. Which is located in Tianyuan District, Zhuzhou City-The Economic Centre of Changsha Zhuzhou and Xiangtan Cities Group. It is a large high-t tech chemical enterprise which specialized in fine chemicals, flavors and fragrances, food additives, pharmaceutical raw material and intermediates. Companies affiliated factory has advanced production equipment and plants, perfect quality assurance and control system, whole set of High Pressure Liquid Chromatography/Gas Chromatography/UV Spectrophotometer to conduct effective product analysis and monitoring. Company factory has passed ISO9001 quality system certification and international KOSHER certification.
Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. Based in chemical industry, lead by food chemical market. Complete e-commerce networks make guarantee for timely service to the world customers. To meet the needs of customers, each product is elite, which is recommended and selected by professional and experienced technicals for customers. The company has independent import and export rights, products exported to foreign markets with high quality and good service, established good business relationship with other countries in Europe, America, Asia, etc. All the staffs will make unremitting efforts to strive for outstanding quality, make excellent brand and service the market by first-class products.
